1. Cancer nanotechnology

My research in cancer nanotechnology focuses on developing and optimizing nanoscale systems for cancer therapy. By designing nanoparticles like albumin-based nanocarriers and pullulan nanoparticles, I aim to enhance the delivery and efficacy of therapeutic agents such as berberine, evodiamine, and plumbagin while minimizing side effects. These nanomaterials improve drug stability, bioavailability, and controlled release, ultimately leading to more precise and effective cancer treatments.

2. Targeted drug delivery

In targeted drug delivery, my research is focused on developing systems that deliver therapeutic agents precisely to cancer cells, sparing healthy tissues. By conjugating targeting ligands such as folate and biotin, targeted delivery can be significantly enhanced. Examples include folate-functionalized and biotin-functionalized albumin nanoparticles, which are engineered to deliver therapeutic agents like berberine, evodiamine, and plumbagin directly to cancer cells. These advanced systems improve drug delivery efficiency, reduce toxicity, and lead to better therapeutic outcomes.

3. DNA nanotechnology

I joined IIT Gandhinagar as a Post-Doctoral Fellow, where my research focuses on the synthesis of DNA-based nanostructures. These engineered DNA nanostructures serve as versatile platforms for drug delivery, enabling precise and controlled therapeutic transport. Additionally, they have potential applications in stem cell differentiation by providing biomimetic cues to regulate cellular fate. Beyond drug delivery, these nanosystems are being explored for bioimaging, offering high-resolution tracking of molecular interactions within biological systems. We are actively working towards harnessing the potential of DNA nanotechnology for advancing biomedical applications.